Research Article

Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers

Figure 2

Index of residues closest to the POPC membrane surface as a function of time. A residue is considered to be the one closest to the bilayer surface if the -position of its centroid is the smallest relative to the average -position of the phosphorus atoms. In water solution, the closest residue index varies with time; once the peptide adsorbs to the membrane surface, the index of the residue closest to the POPC bilayer rarely changes.