Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy

Figure 5

Flow cytometric data of kidneys. Macrophages were defined as PI^-CD45⁺CD11b⁺F4/80⁺ cells in the kidney. The final gating panel of CD11b- and F4/80-positive cell cluster is shown (a). Macrophage % in the kidney (b) and the total number of the macrophages (c) were calculated. Nondiabetic control (Control) (), diabetic mice without treatment (DM) (), diabetic mice with insulin treatment (DM + Ins) (), diabetic mice with salicylate treatment (DM + Sal) (), and diabetic mice with pyridoxamine treatment (DM + Pyrid) (). Values are mean ± SEM.

(a)

(b)

(c)