Microflora Disturbance during Progression of Glucose Intolerance and Effect of Sitagliptin: An Animal Study

Table 2

Statistical analysis was performed by Wilcoxon Signed-Rank test. Data of normal, obesity, diabetes, and sitagliptin are relative abundance (percentage) of all sequences in each group ( group obesity versus normal; group diabetes versus obesity; group diabetes versus sitagliptin).

Taxonomy	Normal (%)	Obesity (%)	Diabetes (%)	Sitagliptin (%)
Bacteroides (genus)	1.4	0.2	0.6	5.4	0.013	0.022	0.005
Prevotellaceae (family)	9.9	1.8	6.8	9.2	0.005	0.001
Blautia (genus)	0.2	0.8	7.1	0.3	0.012	0.005	0.005
Roseburia (genus)	0.7	0.9	0.3	0.5		0.042
Ruminococcus (genus)	2.5	1.4	0.6	1.9		0.025	0.007
Clostridium (genus)	1.3	4.6	0.8	0.7	0.014	0.013
Lactobacillus (genus)	22.3	22.5	13.0	6.7			0.028
Bacillus (genus)	4.6	4.4	6.0	0			0.005
Bifidobacterium (genus)	0.024	0.005	0.002	0.085			0.007
Parabacteroides (genus)	0.2	0.02	0.1	0.6	0.008	0.024	0.005