Effects of a Patient-Provider, Collaborative, Medication-Planning Tool: A Randomized, Controlled Trial
Table 8
Stratified analysis by patients’ literacy status for knowledge of and adherence to the noninjectable medication regimen before and after intervention: Medtable versus usual care.
Time
Health literacy
Medtable
Usual care
Unadjusted intervention effect (ITT)
Mean (SD)
Mean (SD)
OR (95% CI)
value
Combined verbal knowledge of the regimen for all questions
Baseline, preintervention
Limited
0.81 (0.17)
0.82 (0.17)
0.89 (0.66, 1.20)
0.4457
Adequate
0.81 (0.18)
0.80 (0.18)
1.07 (0.91, 1.25)
0.4332
Immediate, postintervention
Limited
0.82 (0.15)
0.82 (0.16)
0.92 (0.68, 1.24)
0.5775
Adequate
0.81 (0.18)
0.79 (0.18)
1.13 (0.96, 1.32)
0.1341
Month 3
Limited
0.82 (0.16)
0.81 (0.17)
1.06 (0.78, 1.44)
0.6997
Adequate
0.80 (0.19)
0.80 (0.17)
1.06 (0.90, 1.25)
0.4644
Month 6
Limited
0.80 (0.17)
0.83 (0.19)
0.94 (0.69, 1.28)
0.6845
Adequate
0.81 (0.19)
0.79 (0.18)
1.14 (0.97, 1.34)
0.1061
Combined demonstration knowledge of the regimen for all 4 questions
Baseline, preintervention
Limited
0.86 (0.15)
0.87 (0.16)
0.83 (0.59, 1.17)
0.2828
Adequate
0.85 (0.15)
0.84 (0.16)
1.08 (0.91, 1.29)
0.3790
Immediate, postintervention
Limited
0.87 (0.14)
0.88 (0.14)
0.77 (0.54, 1.09)
0.1399
Adequate
0.86 (0.15)
0.84 (0.16)
1.17 (0.98, 1.40)
0.0838
Month 3
Limited
0.86 (0.15)
0.86 (0.16)
1.01 (0.72, 1.43)
0.9444
Adequate
0.86 (0.15)
0.85 (0.14)
1.09 (0.91, 1.30)
0.3630
Month 6
Limited
0.86 (0.15)
0.89 (0.13)
0.88 (0.62, 1.25)
0.4740
Adequate
0.87 (0.14)
0.86 (0.14)
1.14 (0.95, 1.37)
0.1711
Combined knowledge of the indication for drugs in the regimen, “what is the medicine for?”
Baseline, preintervention
Limited
0.83 (0.26)
0.83 (0.24)
1.09 (0.79, 1.50)
0.6025
Adequate
0.89 (0.19)
0.88 (0.19)
1.04 (0.85, 1.27)
0.6921
Immediate, postintervention
Limited
0.93 (0.14)
0.84 (0.23)
2.44 (1.66, 3.59)
<0.0001
Adequate
0.95 (0.12)
0.89 (0.18)
2.20 (1.72, 2.82)
<0.0001
Month 3
Limited
0.94 (0.13)
0.83 (0.24)
2.56 (1.73, 3.80)
<0.0001
Adequate
0.96 (0.11)
0.90 (0.17)
2.33 (1.79, 3.04)
<0.0001
Month 6
Limited
0.94 (0.11)
0.85 (0.23)
2.29 (1.53, 3.44)
<0.0001
Adequate
0.97 (0.09)
0.92 (0.16)
2.51 (1.87, 3.37)
<0.0001
Regimen adherence score
Baseline, preintervention
Limited
0.76 (0.28)
0.80 (0.24)
0.68 (0.51, 0.90)
0.0077
Adequate
0.81 (0.25)
0.83 (0.22)
0.91 (0.77, 1.07)
0.2438
Month 3
Limited
0.80 (0.21)
0.80 (0.19)
0.97 (0.74, 1.27)
0.8269
Adequate
0.83 (0.19)
0.81 (0.20)
1.15 (0.98, 1.34)
0.0858
Month 6
Limited
0.78 (0.22)
0.76 (0.18)
0.99 (0.77, 1.28)
0.9656
Adequate
0.81 (0.19)
0.75 (0.21)
1.23 (1.07, 1.42)
0.0040
REALM: Rapid Estimate of Adult Literacy in Medicine. Patients with limited literacy had REALM scores less than 61. Adequate literacy was a REALM score of 61 and above. ITT: intention-to-treat analysis.
