Research Article
Association of Haemostatic and Inflammatory Biomarkers with Nephropathy in Type 1 Diabetes Mellitus
Table 1
Characteristics of type 1 diabetic patients with and without chronic kidney disease.
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Normally distributed data were expressed as mean ± SD and compared by -test. Not normally distributed data were expressed as median (percentiles 25%–75%) and compared by Mann-Whitney test. Categorical variables were expressed as frequencies (%) and compared using the chi-square test (). Body mass index (BMI), time of diagnosis, HbA1c, interferon gamma (INF-γ), von Willebrand factor (VWF), ADAMTS13 activity, and VWF/ADAMTS13 activity ratio were normally distributed. Age, creatinine, urinary albumin excretion (UAE), glomerular filtration rate (GFR), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10), ADAMTS13 antigen, VWF/ADAMTS13 antigen ratio, ADAMTS13 activity/antigen ratio, and D-Dimer were not normally distributed. NS = not significant. CKD = chronic kidney disease. AAS = acetylsalicylic acid. ACEi = angiotensin converting enzyme inhibitor. |