An Alteration of Lymphocytes Subpopulations and Immunoglobulins Levels in Patients with Diabetic Foot Ulcers Infected Particularly by Resistant Pathogens

Table 4

The differences in selected parameters of humoral immunity between the study groups.

Evaluated parameters	Patients with DFUs ()	Diabetic controls ()	value
IgM (g/L)	1.1 ± 0.82	0.94 ± 0.42	NS
IgA (g/L)	3.56 ± 1.32	2.62 ± 1
IgG (g/L)	12.24 ± 3.19	10.83 ± 1.69
IgG1 (g/L)	6.85 ± 2.19	5.3 ± 1.28
IgG2 (g/L)	4.12 ± 1.85	4.12 ± 1.4	NS
IgG3 (g/L)	0.81 ± 0.51	0.62 ± 0.27
IgG4 (g/L)	0.47 ± 0.4	0.43 ± 0.38	NS
Deficit of IgG1 (<3,82 g/L)	2/68 (3%)	3/34 (9%)	NS
Deficit of IgG2 (<2,42 g/L)	15/68 (22%)	5/34 (15%)	NS
Deficit of IgG3 (<0,22 g/L)	0	0	NS
Deficit of IgG4 (<0,04 g/L)	3/68 (4%)	2/34 (6%)	NS

Data are presented as means ± SD; patients with DFUs (diabetic foot ulcers; ); age, sex, and type of diabetes matched diabetic controls (); Ig: immunoglobulin; NS: nonsignificant; value of significance between patients with DFUs and diabetic controls determined using -test or Mann–Whitney test.