Journal of Diabetes Research / 2016 / Article / Tab 4

Research Article

Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity

Table 4

Overall accuracy and ROC analyses of fibrinogen and other markers of inflammation to predict amputation from DFU.

Cut-offAUCSensitivity (%)Specificity (%) NPV (%)PPV (%)ACC (%)

Fibrinogen5.130.858 (0.767, 0.950)80.982.689.078.683.6
CRP28.180.812 (0.684, 0.941)73.789.187.967.680.1
WBC9.870.765 (0.643, 0.888)57.984.878.241.970.2
Neutrophil7.860.771 (0.653, 0.888)52.689.178.650.073.8

AUC: area under curve; ACC: accuracy; NPV: negative predictive value; PPV: positive predictive value; WBC: white blood cells; CRP: C-reactive protein.

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