Training Does Not Alter Muscle Ceramide and Diacylglycerol in Offsprings of Type 2 Diabetic Patients Despite Improved Insulin Sensitivity

Table 2

Muscle ceramide subspecies and total content before and after 10 weeks of endurance training in T2D offsprings and matched controls.

Ceramide	Control; ()			Offspring; ()			value
Subspecies	Pre	Post	%	Pre	Post	%	Training main effect	Training × group interaction
C14:0			−11.5			35.1	0.335	0.268
C16:0			−33.2			−3.22	0.251	0.082
C18:0			−2.08			−0.28	0.830	0.426
C18:1			−12.4			5.80	0.670	0.292
C20:0			−32.0			−0.01	0.384	0.286
C22:0			−14.8			−6.93		0.294
C24:0			−11.5			35.1	0.335	0.268
C24:1			0.94			−8.71	0.251	0.323
Mean %
Total cer.			−4.27			−4.31	0.272	0.579

Data are means ± SEM. All data are given as pmol/mg wet weight. The statistics are based on due to failed normality testing. Pre versus post main effect, (). The % delta calculated as the relative change from baseline.