Subclinical Alterations of Cardiac Mechanics Present Early in the Course of Pediatric Type 1 Diabetes Mellitus: A Prospective Blinded Speckle Tracking Stress Echocardiography Study

Figure 1

Peak systolic global left ventricular strain rate in relation to the duration of disease. Type 1 diabetic children () have increased strain rate both at rest and during exercise when compared to healthy controls (). Patients with a disease duration >4 years (, 42.5%) exhibit higher strain rates than those with a disease duration <4 years (, 57.5%). (a) Peak systolic global LV circumferential strain rate. (b) Peak systolic global LV longitudinal strain rate. ; values were calculated with Mann-Whitney and Wilcoxon signed-rank tests.

(a)

(b)