Journal of Diabetes Research / 2016 / Article / Tab 1

Research Article

Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy

Table 1

Clinical characteristics and levels of MDA-ox LDL of diabetic patients with diabetic retinopathy (DR) and without diabetic retinopathy (noDR). The data are expressed as mean (standard deviation (SD)) or (percent (%)).

DRNoDR

Age (years)58.9 (14.4)55.9 (16.3)0.126
Gender0.411
 Women97 (42.4%)50 (47.2%)
 Men132 (57.6%)56 (52.8%)
BMI (kg/m2)28.8 (5.8)27.2 (5.0)0.056
Diabetes0.636
 Type 198 (43.8%)50 (47.2%)
 Type 2126 (56.2%)56 (52.8%)
 Duration22 (11.5)24.2 (7.8)0.046
BP systolic (mmHg)152.2 (23.6)133.9 (13.5)0.032
BP diastolic (mmHg)83.8 (11.8)83.6 (10.1)0.976
Nephropathy64 (37.2%)16 (15.8%)<0.001
Neuropathy68 (40.5%)19 (18.4%)<0.001
Hypertension171 (76.7%)55 (51.9%)<0.001
Cholesterol (mMol)4.1 (1.1)4.1 (0.9)0.553
LDL (mMol)2.3 (0.9)2.1 (0.8)0.122
HDL (mMol)0.9 (0.5)1.1 (0.5)<0.001
Triglycerides (mMol)1.2 (1.4)0.6 (0.8)<0.001
Creatinine (μMol)102 (82.8)72.9 (21.8)<0.001
Glucose (mMol)8.9 (4.0)8.0 (2.9)0.029
HbA1c (%)8.5 (1.8)7.7 (1.3)<0.001
MDA-ox IgG6827 (5397)7177 (5056)0.579
MDA-ox IgM3316 (4489)3536 (2933)0.644
MDA-ox IgA81.3 (45.4)76.1 (48.2)0.346

BMI: body mass index, BP: blood pressure, HbA1c: glycated hemoglobin, HDL: high-density lipoprotein, and LDL: low-density lipoprotein.