Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

Figure 4

Primary sequences of human IAPP, Pramlintide, and four rationally designed sequences with improved solubility, denoted by Seq-A through Seq-D. The final sequence, denoted by hIAPP, represents a family of designed bioactive analogs of human IAPP in which one of the Asn residues indicated with a () has been glycosylated.