Research Article

Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes

Table 1

Gene Ontology biological process categories enriched by genes differentially expressed in DM relative to controls.

Gene Ontology IDBiological process

Enrichment score: 8.38
GO:0051082Unfolded protein binding
GO:0006457Protein folding

Enrichment score: 4.08
GO:0006412Translation

Enrichment score: 3.95
GO:0015031Protein transport
GO:0045184Establishment of protein localization
GO:0008104Protein localization
GO:0006886Intracellular protein transport
GO:0034613Cellular protein localization
GO:0070727Cellular macromolecule localization
GO:0046907Intracellular transport

Enrichment score: 3.6
GO:0045454Cell redox homeostasis
GO:0019725Cellular homeostasis
GO:0042592Homeostatic process

Enrichment score: 2.7
GO:0006270DNA replication initiation
GO:0006261DNA-dependent DNA replication
GO:0006260DNA replication
GO:0006259DNA metabolic process