Research Article

The Impact of Type 2 Diabetes on the Efficacy of ADP Receptor Blockers in Patients with Acute ST Elevation Myocardial Infarction: A Pilot Prospective Study

Table 2

On-treatment platelet reactivity and prevalence of ADP receptor blocker nonresponders in T2D and ND patients.

On-treatment platelet reactivityT2D patientsND patientsSignificance

LTA with ADP induction (%)
 Sample 157.2 ± 26.450.3 ± 22.3NS
 Sample 245.9 ± 31.337.0 ± 20.8NS
PRI of VASP phosphorylation (%)
 Sample 159.4 ± 30.960.0 ± 25.2NS
 Sample 233.9 ± 25.338.6 ± 29.3NS

ADP receptor blocker nonresponders (% of patients/number of patients)T2D patientsND patientsSignificance

ADP receptor blocker nonresponders
 Sample 152.4%/11 patients56.5%/26 patientsNS
 Sample 233.3%/7 patients30.4%/14 patientsNS