Research Article

The Impact of Type 2 Diabetes on the Efficacy of ADP Receptor Blockers in Patients with Acute ST Elevation Myocardial Infarction: A Pilot Prospective Study

Table 3

Platelet aggregability and PRI of VASP-P in prasugrel- and clopidogrel-treated patients with acute STEMI (analysis of combined T2D and ND patients and analysis of T2D patients, marked as T2D patients).

LTA with ADP induction (%)Prasugrel-treated patientsClopidogrel-treated patientsSignificance

Sample 145.9 ± 26.2%59.2 ± 18.8% < 0.05
Sample 224.9 ± 17.7%51.7 ± 22.8% < 0.001

LTA with ADP induction (%)
T2D patients
Prasugrel-treated T2D patientsClopidogrel-treated T2D patientsSignificance

Sample 143.3 ± 20.663.5 ± 22.8 < 0.05
Sample 222.9 ± 16.960.3 ± 26.6 < 0.01

PRI of VASP-P analysis (%)Prasugrel-treated patientsClopidogrel-treated patientsSignificance

Sample 152.7 ± 29.7%68.9 ± 19.9 < 0.05
Sample 226.3 ± 24.3%51.8 ± 22.8% < 0.01

PRI of VASP-P analysis (%)
T2D patients
Prasugrel-treated T2D patientsClopidogrel-treated T2D patientsSignificance

Sample 146.8 ± 33.578.3 ± 13.0 < 0.05
Sample 218.7 ± 15.756.8 ± 18.7 < 0.01