ClC-3 Expression and Its Association with Hyperglycemia Induced HT22 Hippocampal Neuronal Cell Apoptosis

Figure 1

Influence of high glucose on the morphology of HT22 cells as observed after 24 hours of culture: under inverted microscope the 25 mM glucose (control) group and 30 mM glucose stimulation group displayed spindle or multipolar shaped cells with full and transparent cell body with excellent growth, whereas the 50 mM glucose stimulation group showed a reduction in cell attachment and numbers with a significant decrease in light refraction (scale bar 10 μm).