Teneligliptin Decreases Uric Acid Levels by Reducing Xanthine Dehydrogenase Expression in White Adipose Tissue of Male Wistar Rats

Figure 7

Effects of teneligliptin and DPP-4 on uric acid secretion from 3T3-L1 adipocytes. Serum-starved 3T3-L1 adipocytes were treated without (□) or with teneligliptin (■; 10 μM) and/or DPP-4 (200 ng/mL). Uric acid secretion for 24 hours of incubation in the presence of the indicated concentration of teneligliptin or DPP-4, respectively. Data are the means ± SEM of 3 independent experiments (1 experiment performed with 4 samples). ; versus the value in the absence of teneligliptin.