Research Article

Impact of Pancreatic Rat Islet Density on Cell Survival during Hypoxia

Figure 4

Inflammation. (a) Levels of Cox-2 mRNA expression in islets after 24 hours in culture at 150, 300, and 600IEQ/cm2 under normoxic (PO2 160 mmHg) and hypoxic (PO2 15 mmHg) conditions. (b) Levels of Ho-1 mRNA expression after 24 hours in culture under the specified conditions. (c) IL-6 secretion was measured in islet medium after 24 hours in culture under the specified conditions. compared to the control, compared to 150IEQ/cm2 under normoxic conditions, compared to 150IEQ/cm2 under normoxic conditions, and and compared to 150IEQ/cm2 under hypoxic conditions.
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