Ectopic Fat Deposition on Insulin Sensitivity: Correlation of Hepatocellular Lipid Content and M Value

Table 1

Clinical and biochemical characteristics.

	NGT	IGT	T2DM	P value
Sex (male/female)	17/12	7/10	6/7	0.484
Age (year)	47.62 ± 8.48	53.24 ± 6.55	50.92 ± 7.32	0.060
BMI (kg/m^2)	25.14 ± 3.26	25.92 ± 2.96	26.39 ± 2.76	0.441
WHR	0.89 ± 0.07	0.89 ± 0.05	0.94 ± 0.07^†‡	0.036
SBP (mmHg)	117.45 ± 11.22	123.24 ± 15.77	124.69 ± 14.10	0.181
DBP (mmHg)	74.00 ± 9.17	74.94 ± 8.83	77.85 ± 10.21	0.468
FPG (mmol/L)	5.02 ± 0.45	5.09 ± 0.36	7.48 ± 1.60^†‡	0.000
PG30 min (mmol/L)	8.87 ± 1.66	10.22 ± 1.65^†	13.58 ± 2.22^†‡	0.000
PG2 h (mmol/L)	5.53 ± 1.00	8.97 ± 0.95^†	15.66 ± 2.89^†‡	0.000
HBA1c (%)	5.52 ± 0.53	6.06 ± 0.30^†	7.28 ± 1.23^†‡	0.000
CHOL (mmol/L)	5.12 ± 0.96	6.04 ± 1.02^†	5.41 ± 1.07	0.014
TG (mmol/L)	1.19 (0.60–1.75)	1.57 (1.27–1.95)	2.03 (1.44–3.70)^†	0.002
HDL-c (mmol/L)	1.26 (1.05–1.52)	1.27 (1.07–1.36)	1.05 (0.93–1.26)	0.074
LDL-c (mmol/L)	3.31 ± 0.91	4.37 ± 1.00^†	3.75 ± 0.96	0.002
eGFR	102.18 ± 24.11	98.08 ± 13.15	98.79 ± 22.00	0.785
(mL/min × 1.73 m^2)
ALT (U/L)	19.00 (14.00–25.00)	21.00 (19.00–24.00)	39.50 (27.00–48.00)^†‡	0.003
AST (U/L)	20.00 (19.00–23.00)	21.00 (19.00–27.00)	28.50 (17.00–33.00)	0.102
GGT (U/L)	23.00 (20.00–35.00)	28.00 (20.00–40.00)	49.00 (34.00–83.00)^†	0.003

Data are presented as the mean ± SD or median (25th–75th). ^†NGT versus IGT and T2DM , ^‡IGT versus T2DM . BMI: body mass index, WHR: waist-to-hip ratio, SBP: systolic blood pressure, DBP: diastolic blood pressure, FPG: fasting plasma glucose, PG30 min: 30 min plasma glucose, PG2 h: 2 h plasma glucose, HBA1c: hemoglobin A1c, CHOL: total cholesterol, TG: triglyceride, HDL-c: high-density lipoprotein, LDL-c: low-density lipoprotein, ALT: alanine aminotransferase, AST: aspartate aminotransferase, GGT: gamma-glutamyl transpeptidase, and eGFR: estimated glomerular filtration rate.