Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 1

Characteristics of studies about IL-6 (pg/mL) included in this meta-analysis.

Author	Year	Country	Case				Control				NOS score
			SZ	M/F	Mean	SD	SZ	M/F	Mean	SD
Plomgaard [34]	2007	Denmark	96	72/24	1.63	1.22	103	70/33	1.27	1.04	7
Volpe [35]	2014	Brazil	29	10/19	119.1	23.3	16	5/11	97.6	13.5	8
Yeo [36]	2010	Korea	55	27/28	2.3	0.35	488	257/231	1.8	0.11	8
Kado [37]	1999	Japan	57	NR	3.48	3.29	15	NR	0.784	0.9	7
Lukic [38]	2014	Serbia	30	NR	11.77	6.09	15	NR	3.48	1.48	8
Lukic [38]	2014	Serbia	30	NR	15.46	5.15	15	NR	3.48	1.48	8
Hansen [39]	2012	Denmark	8	NR	4.6	5.2	8	NR	1.4	1.15	7
Andriankaja [40]	2009	USA	30	NR	1.5	1.4	310	NR	1.8	2.3	8
Andriankaja [40]	2009	USA	50	NR	2.9	3.2	310	NR	1.8	2.3	8
Guzel [41]	2013	Turkey	28	NR	3.21	1.24	30	19/14	1.73	0.93	8
Guzel [41]	2013	Turkey	17	NR	6.67	2.67	30	19/14	1.73	0.93	8
Aso [42]	2003	Japan	42	22/20	3.15	1.53	48	NR	1.29	0.52	7
Lim [43]	2004	England	56	31/25	1.9	8.02	39	21/18	1	1.59	8
Lim [43]	2004	England	41	30/11	2.6	26.95	39	21/18	1	1.59	7
Hui [44]	2015	China	48	20/28	16.17	8.36	20	13/7	5.2	2.03	8
Daniele [45]	2014	USA	17	13/4	2.1	0.4	15	7/8	1.7	0.4	8
Głowińska [46]	2003	Polish	28	NR	6.5	1.4	15	NR	2.3	2.3	7

DM: diabetes mellitus; SZ: sample size; M/F: man/female; SD: standard deviation; NR: not reported. T2DM with complication and data (mean ± SD) converted from mean (95% CI).