Journal of Diabetes Research

Research Article

Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 2

Characteristics of studies about TGF-β (g/L) included in this meta-analysis.


Author	Year	Country	Case				Control				NOS score
Author	Year	Country	SZ	M/F	Mean	SD	SZ	M/F	Mean	SD	NOS score

Azar [47]	1999	Lebanon	26	8/18	0.558	0.107	27	10/17	0.593	0.064	8
Azar [48]	2000	Lebanon	8	3/5	10.8	2.3	15	9/6	4.1	0.5	8
Azar [48]	2000	Lebanon	9	2/7	9.9	2.8	15	9/6	4.1	0.5	8
Azar [48]	2000	Lebanon	8	5/3	10.7	2.2	15	9/6	4.1	0.5	8
Jun-Wen [49]	2007	China	61	35/26	315.9	224.59	19	10/9	68.47	31.75	7
Chi [50]	2013	China	20	11/9	18.55	2.67	18	10/8	8.97	4.087	8
Chi [50]	2013	China	20	9/11	19.04	2.87	18	10/8	8.97	4.087	8
Chi [50]	2013	China	21	13/8	18.12	3.17	18	10/8	8.97	4.087	8
Ehnert [51]	2015	Germany	14	7/7	35.3	2.4	13	7/6	39.5	1.4	8
Changxin [52]	2007	China	34	24/10	36.2	8.8	35	24/11	34.4	8.2	7
Changxin [52]	2007	China	31	21/10	69.4	12.8	35	24/11	34.4	8.2	7
Hellmich [53]	2000	Germany	35	16/19	9.5	2.1	12	5/7	0.24	0.03	8
Hellmich [53]	2000	Germany	23	8/15	10.8	2.1	12	5/7	0.24	0.03	8
Herder [54]	2009	Germany	460	255/205	35.8	0.4	1474	724/750	35	0.2	8
Hai-bing [55]	2001	China	14	7/7	35.02	6.7	15	7/8	23.95	8.01	6
Hai-bing [55]	2001	China	13	5/8	58.58	9.56	15	7/8	23.95	8.01	6
Hai-bing [55]	2001	China	18	9/9	39.31	5.35	15	7/8	23.95	8.01	6
Zhen-zuo [56]	2005	China	27	14/13	41	15.57	18	9/9	10.04	5.33	7
Zhen-zuo [56]	2005	China	12	7/5	66.35	18.04	18	9/9	10.04	5.33	7
Zhen-zuo [56]	2005	China	18	9/9	53.31	15.64	18	9/9	10.04	5.33	7
Rui-Ji [57]	2011	China	32	NR	35	5	20	NR	25	5	6
Rui-Ji [57]	2011	China	31	NR	69	7	20	NR	25	5	6
Rui-Ji [57]	2011	China	32	NR	54	6	20	NR	25	5	6
Da-wei [58]	2013	China	15	NR	234.2	29.8	45	NR	69.4	12.5	7
Da-wei [58]	2013	China	32	NR	155.6	19.3	45	NR	69.4	12.5	7
Pfeiffer [59]	1996	Germany	44	22/22	7.9	1	28	16/12	3.1	0.4	8
Yan-Jun [60]	2002	China	34	16/18	147.03	22.57	35	17/18	136.97	37.96	7
Yan-Jun [60]	2002	China	31	15/16	170.65	18.74	35	17/18	136.97	37.96	7
Yaping [61]	2008	China	44	NR	35.4	7.1	35	NR	32.5	6.8	7
Yaping [61]	2008	China	32	NR	68.2	12.5	35	NR	32.5	6.8	7
Ye-Sheng [62]	2005	China	92	42/50	36.89	9.75	105	50/55	25.46	7.88	6
Ye-Sheng [62]	2005	China	91	40/51	41.57	10.55	105	50/55	25.46	7.88	6
Ming-bin [63]	2002	China	15	NR	25.85	6.09	15	8/7	21.4	5.62	6
Ming-bin [63]	2002	China	18	NR	38.53	3.98	15	8/7	21.4	5.62	6
Ming-bin [63]	2002	China	16	NR	31.15	3.51	15	8/7	21.4	5.62	6
Chun-Yan [64]	2005	China	92	NR	45.57	21.78	20	NR	24.58	12.61	7
Yener [23]	2008	Turkey	39	18/21	29.84	7.04	30	16/14	11.37	4.06	8
Yuan [65]	2011	China	51	37/14	1.7399	0.4846	55	40/15	2.1045	0.5327	7
Wei-jie [66]	2007	China	36	19/17	23.35	3.7	40	23/17	20.35	3.7	7
Wei-jie [66]	2007	China	45	25/20	55.28	6.8	40	23/17	20.35	3.7	7
Wei-jie [66]	2007	China	45	23/22	41.31	4.3	40	23/17	20.35	3.7	7
Zhou [67]	2005	China	30	NR	31.12	12.39	30	NR	29.4	10.62	8
Zhou [67]	2005	China	30	NR	136.6	21.45	30	NR	29.4	10.62	8
Zhou [67]	2005	China	30	NR	79.63	15.96	30	NR	29.4	10.62	8

DM: diabetes mellitus; SZ: sample size; M/F: man/female; SD: standard deviation; NR: not reported. T2DM with different complication; T2DM with different duration limited.