Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 4

Characteristics of studies about the percentage of CD4⁺CD25⁺Foxp3⁺Tregs (%) in the CD4⁺ lymphocyte included in this meta-analysis.

Author	Year	Country	Case				Control				NOS score
			SZ	M/F	Mean	SD	SZ	M/F	Mean	SD
Haseda [70]	2013	Japan	20	8/12	4.94	1.78	30	10/20	5.36	1.54	8
Li [71]	2011	China	18	14/4	2.8	8.54	18	12/6	5.01	0.13	7
Li [72]	2014	China	15	NR	2.32	0.5	21	13/8	4.07	1.39	8
Li [72]	2014	China	23	NR	2.91	0.73	21	13/8	4.07	1.39	8
Jing [73]	2009	China	60	33/27	3.2733	1.5835	15	8/7	3.6216	0.6938	8
Zhang [74]	2009	China	17	9/8	5.02	3.59	15	8/7	5.07	3.26	7
Zhang [75]	2012	China	16	11/5	2.21	0.92	19	7/12	2.32	0.6	6

DM: diabetes mellitus; SZ: sample size; M/F: man/female; SD: standard deviation; NR: not reported. T2DM with different complication.