Abnormal Glucose Tolerance Is Associated with a Reduced Myocardial Metabolic Flexibility in Patients with Dilated Cardiomyopathy
Table 1
Clinical characteristics of the study populations.
N-AGT
DCM-NGT
DCM-AGT
5
5
5
Age (year)
62 ± 6
55 ± 3
60 ± 6
Males/females ()
3/2
4/1
3/2
Angina ()
5
2
1
NYHA class II/III ()
1/0
3/2
3/2
LV mass (g)
175 ± 16
288 ± 27
292 ± 43
LVEF (%)
56 ± 2
34 ± 2
31 ± 1
LVEDD (mm)
51 ± 2
64 ± 2
66 ± 2
BNP (pg/mL)
20 ± 7
98 ± 22
104 ± 30
NT-proBNP (pg/mL)
128 ± 37
598 ± 130
604 ± 127
Body mass index (kg/m2)
28 ± 2
29 ± 2
30 ± 2
Fasting insulin (pmol/L)
77 ± 8
69 ± 9
84 ± 10
Fasting glucose (mmol/L)
5.6 ± 0.2
5.4 ± 0.2
5.8 ± 0.2
OGTT 2 h glucose (mmol/L)
10.8 ± 1.1
6.0 ± 0.6
10.9 ± 0.7
Triglycerides (mmol/L)
0.66 ± 0.10
0.65 ± 0.19
1.14 ± 0.20
β-blockers ()
3
5
5
ACE-inhibitors/AT-1 antagonists ()
4
5
5
Antialdosteronic agents ()
0
3
4
Furosemide ≥25 mg/die ()
1
5
5
LV mass: left ventricular mass; LVEF: left ventricular ejection fraction; LVEDD: left ventricular end diastolic diameter. for the comparison with N-AGT. for the comparison between DCM-NGT and AGT.
