Research Article

Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice

Table 2

Effect of NPA on serum levels of glucose, insulin, and insulin sensitivity index in all groups of rats.

GroupFBG ( value)
(mmol/L)
Insulin ( value)
(mU/L)
HOMA-IR ( value)

Control 3.41 0.3721.15 3.263.23 0.75
NAFLD 4.61 0.5237.57 3.217.65 1.34
NPA (200 mg/kg)4.34 0.4935.89 5.187.07 1.45
NPA (400 mg/kg)4.12 0.2830.69 3.865.60 0.61
NPA (600 mg/kg) 3.73 0.2726.71 3.114.53 0.36
Positive group3.65 0.1325.58 3.264.16 0.57

Different letters (a, b, c, or d) in the same column represent significant differences between the treated groups ().