Reversal of Early Diabetic Nephropathy by Islet Transplantation under the Kidney Capsule in a Rat Model

Figure 3

TEM detection of renal tissues and immunohistochemical staining for synaptopodin in podocytes. (a) TEM detection of podocytes and the glomerular filtration barrier. (b) Immunohistochemical staining for synaptopodin, which stains podocytes specifically, to measure the density of podocytes. (c) Measurement of the thickness of the GBM in each group, and . (d) Comparison of the IOD/area of synaptopodin immunohistochemical staining for each group, and . IOD/area, integrated optical density/area. The mean of IOD/area of positive staining was used to accurately measure the degree of positive expression in immunohistochemical staining. Model group: diabetic nephropathy model rats established at 12 weeks.

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