Research Article

Gmelina arborea Roxb. (Family: Verbenaceae) Extract Upregulates the β-Cell Regeneration in STZ Induced Diabetic Rats

Table 1

Blood/serum glycemic parameters in diabetic rats after 30 days of treatment.

TreatmentGlycated hemoglobin (%)Fructosamine (µmol/L)Insulin (µIU/mL)C-peptide (ng/mL)

Healthy untreated4.86 ± 0.10221.88 ± 3.1014.23 ± 0.449.53 ± 0.80
Diabetic untreated9.00 ± 0.09405.39 ± 2.786.23 ± 0.095.75 ± 0.80
G. arborea (1.00 g/kg)6.20 ± 0.06292.30 ± 2.199.80 ± 0.107.98 ± 0.07
Glibenclamide (0.50 mg/kg)5.38 ± 0.06230.08 ± 0.9911.75 ± 0.028.80 ± 0.01

The values are expressed as mean ± SEM (/group). Statistically significant from streptozotocin induced diabetic control rats at (ANOVA followed by Dunnett’s test).