Modeling and Measurement of Correlation between Blood and Interstitial Glucose Changes

Figure 4

Diffusion and delay of glucose from blood to ISF in mice. (a) Prediction of ISF glucose changes following different diffusion distances (). (b) Projection of measured ISF glucose changes to the predicted time course of ISF glucose changes in semilog curves. A better fitting time point was found in a diffusion distance of 24 μm in mice, indicating a time delay for glucose changes in ISF compared with blood glucose changes.

(a)

(b)