Nutrition and Physical Activity in Nonalcoholic Fatty Liver Disease

Figure 1

Spectrum of NAFLD. Obesity, genetic factors, and insulin resistance (IR) contribute to fat deposition in the liver. Approximately 30% of patients with NAFLD have NASH, which involves the presence of various degrees of inflammation and fibrosis, and can progress to cirrhosis in 20–25% of cases within 20 years. An unknown percentage of cases develop HCC. Adapted from Trauner et al., 2010 [9].