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Journal of Diabetes Research
Volume 2016, Article ID 4786925, 8 pages
http://dx.doi.org/10.1155/2016/4786925
Research Article

Assessment of Left Ventricular Structural Remodelling in Patients with Diabetic Cardiomyopathy by Cardiovascular Magnetic Resonance

1Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
2Department of Endocrinology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
3Department of Radiology, Xuanwu Hospital, Beijing 100053, China

Received 3 April 2016; Accepted 26 April 2016

Academic Editor: Nikolaos Papanas

Copyright © 2016 Yongning Shang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Diabetic cardiomyopathy (DCM) is always accompanied with alteration of left ventricular structure and function. The aims of this study were to assess the structural remodelling in patients with DCM by cardiovascular magnetic resonance (CMR) and correlation of structural remodelling with severity of DCM. Methods. Twenty-five patients ( years, 52.0% males) with DCM and thirty-one normal healthy controls ( years, 45.2% males) were scanned by CMR cine to assess function and structure of left ventricular. Length of diabetic history and results of cardiac echocardiography (E′, A′, and E′/A′) were also measured. Results. Compared with normal controls group, DCM group was associated with significantly increased ratio of left ventricular mass at end diastole to end-diastolic volume (MVR) () and no significant difference was in mass at end diastole (). The ratio correlated with both length of diabetic history and echocardiographic Doppler tissue imaging E′ (all ). Conclusions. CMR can be a powerful technique to assess LV remodelling, and MVR may be considered as an imaging marker to evaluate the severity of LV remodelling in patients with DCM.