Exogenous Angiotensin I Metabolism in Aorta Isolated from Streptozotocin Treated Diabetic Rats

Table 1

Concentrations of the products of metabolism of exogenously added (to a final concentration of 1 µM) angiotensin I by the aorta fragments of streptozotocin and saline treated animals (pg/mg of dry tissue; median [25th, 75th percentile]). values are from Kruskal-Wallis nonparametric tests.

Analyte	Concentration in streptozotocin treated rats (), pg/mg of dry tissue; median [25th, 75th percentile]	Concentration in control rats (), pg/mg of dry tissue; median [25th, 75th percentile]	value
Angiotensin I	773.41 [667.48, 877.49]	690.10 [546.29, 825.94]	0.42
Angiotensin II	13.50 [10.46, 14.89]	8.27 [7.47, 10.75]	0.02
Angiotensin III	3.80 [3.34, 4.89]	3.31 [2.63, 3.72]	0.20
Angiotensin IV	1.14 [0.84, 1.53]	1.60 [1.13, 1.73]	0.25
Angiotensin (1–9)	3.37 [1.94, 4.15]	4.12 [1.32, 5.10]	0.41
Angiotensin (1–7)	2.39 [1.81, 3.14]	2.20 [1.92, 3.21]	0.82
Angiotensin (1–5)	1.06 [0.86, 1.72]	1.22 [0.77, 1.95]	0.91