Small Mouse Islets Are Deficient in Glucagon-Producing Alpha Cells but Rich in Somatostatin-Secreting Delta Cells

Figure 3

Double immunostaining of a big islet (a) and a small islet (b) in the pancreas for somatostatin (red) and insulin (brown). Immunostaining of an isolated big islet (c) and an isolated small islet (d) for somatostatin (brown). The somatostatin-producing δ-cells are located in both the core and periphery of the islets. Scale bars represent 50 μm.

(a)

(b)

(c)

(d)