Journal of Diabetes Research / 2016 / Article / Tab 1

Research Article

Small Mouse Islets Are Deficient in Glucagon-Producing Alpha Cells but Rich in Somatostatin-Secreting Delta Cells

Table 1

Proportions of α- and δ-cells in small and big islets. Areas stained for glucagon and somatostatin in the largest cross section of small (<60 µm) and big (>100 µm) islets. The data refer to observations made in paraffin sections of pancreas and isolated islets. All values are given as means ± SEM. compared with small islets stained for glucagon in the pancreas. compared with small islets stained for somatostatin in the pancreas. compared with small isolated islets stained for glucagon. compared with small isolated islets stained for somatostatin.

Islets in pancreasIsolated islets
Small isletsBig isletsSmall isletsBig islets

Glucagon
 Number of animals5564
 Number of islets52655244
 Area stained for glucagon (%)3.22 ± 0.518.61 ± 0.500.11.43 ± 0.28

Somatostatin
 Number of animals5545
 Number of islets68513550
 Area stained for somatostatin (%)4.60 ± 0.483.37 ± 0.22#5.71 ± 0.583.54 ± 0.24

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