Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice

Figure 2

Diabetic albuminuria was reduced by knockout of the ACKR2 gene at 2, 4, and 6 months of age. Urine albumin and creatinine were determined as described in Methods. indicates versus OVE. Comparisons were performed by one-way ANOVA. in each OVE and OVE-ACKR2 group. For FVB , and 6 at 2, 4, and 6 months, respectively. For ACKR2 , and 7 at 2, 4, and 6 months, respectively.

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