Journal of Diabetes Research / 2016 / Article / Tab 2 / Research Article
Comparison of Clinical Trajectories before Initiation of Renal Replacement Therapy between Diabetic Nephropathy and Nephrosclerosis on the KDIGO Guidelines Heat Map Table 2 Clinical characteristics and medications at the initiation of RRT in the two groups.
Diabetic nephropathy Nephrosclerosis 50 (34/16) 50 (35/15) 0.833 Age (years) 67.2 ± 9.6 78.8 ± 6.4 <0.0001 Observational periods (months) 115 ± 57 122 ± 35 0.447 Measurement times (/year) 4.4 ± 2.5 4.4 ± 2.6 0.955 Measurement times (/person) 34 ± 11 37 ± 10 0.109 Body mass index (kg/m2 ) 24.8 ± 2.5 22.1 ± 1.7 <0.0001 Systolic blood pressure (mmHg) 147 ± 15 137 ± 9 <0.0001 Diastolic blood pressure (mmHg) 80 ± 12 73 ± 10 0.0003 Heart rate (bpm) 77 ± 7 76 ± 8 0.541 Mode of renal replacement therapy % ( Hemodialysis 92 (46) 92 (46) — Peritoneal dialysis 8 (4) 8 (4) — Kidney transplantation 0 (0) 0 (0) — Cardiovascular comorbidities % ( 34 (17) 18 (9) 0.069 Ischemic heart disease 28 (14) 12 (6) 0.046 Cerebrovascular disease 6 (3) 4 (2) 0.650 Peripheral artery disease 4 (2) 2 (1) 0.562 Diabetic retinopathy % ( 100 (50) — — Medication % ( Antihypertensive agents Angiotensin receptor blockers 98 (49) 90 (45) 0.093 Angiotensin-converting enzyme inhibitors 14 (7) 4 (2) 0.082 Direct renin inhibitors 8 (4) 2 (1) 0.173 Calcium channel blockers 98 (49) 94 (47) 0.312 Diuretics 98 (49) 92 (46) 0.172 β -blockers 30 (15) 14 (7) 0.054 α -blockers 30 (15) 14 (7) 0.054 Number of antihypertensive agents (per person) 3.76 ± 0.2 3.10 ± 0.1 0.0006 Antidiabetic agents Insulin 38 ( — — Oral hypoglycemic agents 58 ( — — Diet therapy alone 4 ( — — Erythropoiesis stimulating agents 100 (50) 98 (49) 0.319 Statins 80 (40) 78 (39) 0.808 Active vitamin D 94 (47) 92 (46) 0.698
Data are expressed as mean ± SD, %, or
