Journal of Diabetes Research / 2016 / Article / Tab 2

Research Article

Comparison of Clinical Trajectories before Initiation of Renal Replacement Therapy between Diabetic Nephropathy and Nephrosclerosis on the KDIGO Guidelines Heat Map

Table 2

Clinical characteristics and medications at the initiation of RRT in the two groups.

Diabetic nephropathyNephrosclerosis value

(male/female)50 (34/16)50 (35/15)0.833
Age (years)67.2 ± 9.678.8 ± 6.4<0.0001
Observational periods (months)115 ± 57122 ± 350.447
Measurement times (/year)4.4 ± 2.54.4 ± 2.60.955
Measurement times (/person)34 ± 1137 ± 100.109
Body mass index (kg/m2)24.8 ± 2.522.1 ± 1.7<0.0001
Systolic blood pressure (mmHg)147 ± 15137 ± 9<0.0001
Diastolic blood pressure (mmHg)80 ± 1273 ± 100.0003
Heart rate (bpm)77 ± 776 ± 80.541
Mode of renal replacement therapy % ()
 Hemodialysis92 (46)92 (46)
 Peritoneal dialysis8 (4)8 (4)
 Kidney transplantation0 (0)0 (0)
Cardiovascular comorbidities % ()34 (17)18 (9)0.069
 Ischemic heart disease28 (14)12 (6)0.046
 Cerebrovascular disease6 (3)4 (2)0.650
 Peripheral artery disease4 (2)2 (1)0.562
Diabetic retinopathy % ()100 (50)
Medication % ()
Antihypertensive agents
 Angiotensin receptor blockers98 (49)90 (45)0.093
 Angiotensin-converting enzyme inhibitors14 (7)4 (2)0.082
 Direct renin inhibitors8 (4)2 (1)0.173
 Calcium channel blockers98 (49)94 (47)0.312
 Diuretics98 (49)92 (46)0.172
β-blockers30 (15)14 (7)0.054
α-blockers30 (15)14 (7)0.054
Number of antihypertensive agents (per person)3.76 ± 0.23.10 ± 0.10.0006
Antidiabetic agents
 Insulin38 ()
 Oral hypoglycemic agents58 ()
 Diet therapy alone4 ()
Erythropoiesis stimulating agents100 (50)98 (49)0.319
Statins80 (40)78 (39)0.808
Active vitamin D94 (47)92 (46)0.698

Data are expressed as mean ± SD, %, or .