Clinical Study

Effect of Ranirestat on Sensory and Motor Nerve Function in Japanese Patients with Diabetic Polyneuropathy: A Randomized Double-Blind Placebo-Controlled Study

Table 3

Changes from baseline in the summed sensory NCV and individual NCV.

Ranirestat
()
Placebo
()
values

Sensory NCV (m/s)
 Summed sensoryBaseline0.006
Change
 Right sural sensoryBaseline0.088
Change
 Left sural sensoryBaseline0.183
Change
 Proximal median sensoryBaseline0.019
Change
 Distal median sensoryBaseline0.153
Change
Motor NCV (m/s)
 Median motorBaseline0.051
Change
 Tibial motorBaseline0.152
Change

Data shown are mean ± SD change from baseline to last observation carried forward. values were obtained from an ANCOVA model with change from baseline to the last observation and the baseline value as a covariate.