The Four-Herb Chinese Medicine Formula Tuo-Li-Xiao-Du-San Accelerates Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats through Reducing Inflammation and Increasing Angiogenesis

Figure 6

Effect of TLXDS treatment on the vascular endothelial growth factor-A (VEGF-A), platelet-derived growth factor BB (PDGF-BB), interleukin-1β (IL-1-β), and tumor necrosis factor-α (TNF-α) expressions assessed by western blot and real-time PCR analysis. Representative immunoblots of VEGF and PDGF-BB on day 5 after wounding ((a), for each group), IL-1-β and TNF-α on day 11 after wounding ((b), for each group). Quantifications of the bands (c–f). Quantification of VEGF-A, PDGF-BB, IL-1-β, and TNF-α mRNA expression (g–j). Data are presented as means ± SEM. , compared with NC group, and , compared with DM group.

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