Urinary Extracellular Vesicles: Potential Biomarkers of Renal Function in Diabetic Patients

Table 1

Clinical characteristics, blood, and urine biochemistry of study groups: C, CD, and UD.

	C	CD	UD	value
Age; (years)	52 (7)	62	61	0.0683
Gender; (male/female)	6/4	17/7	23/13	—
Serum glucose	5.2			<0.0001
(mmol/L)	(5.0–5.5)	(5.9–7.9)	(7.4–12)
Urine albumin	6			<0.0001
(mg/L)	(4–13)	(2–22)	(12–267)
Urine creatinine	15			0.0054
(mmol/L)	(9–17)	(4–9)	(5–11)
Serum creatinine; (µmol/L)	72; (60–85)	77; (67–98)	79; (62–108)	0.4696
GFR; (mL/min/1.73 m^2)	87; (76–101)	77; (59–95)	79; (59–97)	0.5114
EVs density				0.5013
(number/mL)	()	()	()
EVs mode diameter	106			0.0212
(nm)	(104–110)	(107–118)	(106–112)
EVs mean diameter; (nm)	123 (4)	134	129 (8)	0.0065

in comparison with the control group at .
difference between subgroups CD and UD at .
Bold means statistically significant difference between the three groups at .