Urinary Extracellular Vesicles: Potential Biomarkers of Renal Function in Diabetic Patients
Table 2
Clinical characteristics, blood, and urine biochemistry of study groups: C, RF, and NRF.
C
RF
NRF
value
Age (years)
52 (7)
69
60
0.0027
Gender (male/female)
6/4
15/3
25/17
—
Serum glucose
5.2
<0.0001
(mmol/L)
(5.0–5.5)
(6.5–11)
(6.5–10)
Urine albumin
14
0.0923
(mg/L)
(4–13)
(7–359)
(4–58)
Urine creatinine
15
0.0046
(mmol/L)
(9–17)
(5–8)
(4–11)
Serum creatinine
72
<0.0001
(µmol/L)
(60–85)
(111–123)
(60–84)
GFR
87
<0.0001
(mL/min/1.73 m2)
(76–101)
(39–55)
(73–105)
EVs density
8.7E
0.0361
(number/mL)
()
()
()
EVs mode diameter (nm)
106 (104–110)
111 (105–115)
109 (107–115)
0.1965
EVs mean diameter
122
129
0.0101
(nm)
(120–126)
(123–138)
(126–136)
in comparison with the control group at . difference between subgroups RF and NRF at . Bold means statistically significant difference between the three groups at .
