Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies

Figure 1

Prevalence of Abs against MAP, proinsulin, and ZnT8 homologous peptides in children at risk of T1D and healthy controls. Sera were tested in duplicate for their reactivity against plate-coated peptides: MAP1,4αgb (M1); P (P1); MAP2404 (M2); P (P2); MAP3865 (M3); ZnT (Z3); MAP3865 (M4); ZnT (Z4). Percentage of children with Abs positivity to any of the analyzed peptides is indicated by the first column pair. Dark bars represent children at risk of T1D; light grey bars correspond to HCs.