Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies

Figure 2

Correlation between Abs recognizing MAP and its homologous human epitopes in Sardinian children at risk for T1D. Correlations are shown between Abs against MAP1,4αgb/P (a), MAP2404/P (b), MAP3865/ZnT (c), and MAP3865/ZnT (d) in 23 at-risk children. Each circle represents Abs of one of ARS. The dotted lines indicate the cut-off for positivity used in each assay, as calculated by ROC analysis.

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