Continuous Quadrupole Magnetic Separation of Islets during Digestion Improves Purified Porcine Islet Viability

Figure 1

Schematic diagram of the QMS system used for the continuous purification of islets during digestion. The QMS replaces the collection and purification steps of the islet isolation process with a continuous QMS of labeled islets from the collection stream leaving the digestion chamber. This process streamlines islet preparation, avoids the harmful centrifugation, recombination, and gradient purification steps, and immediately washes and collects the purified islet product. Illustration by Chan A. Huynh.