Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration

Table 3

Comparison of clinical characteristics of subjects with fasting plasma glucose ≥126 mg/dL (≥7.0 mmol/L) stratified by HbA1c < or ≥ 6.5% (48 mmol/mol).

	⁢Diabetes by fasting glucose
	HbA1c < 6.5%; (<48 mmol/mol)	HbA1c ≥ 6.5%; (≥48 mmol/mol)
	139	106
Age, year	61 ± 15	59 ± 15	NS
Gender, female	49 (35.3%)	39 (36.8%)	NS
Body mass index, kg/m^2	31.4 ± 7.2	33.0 ± 7.0	NS
Systolic blood pressure, mmHg	129 ± 20	132 ± 20	NS
Diastolic blood pressure, mmHg	71 ± 13	71 ± 15	NS
Current smoking, yes	33 (23.7%)	34 (32.1%)	NS
Alcohol consumption, yes	98 (70.5%)	69 (65.1%)	NS
Family history of diabetes, yes	61 (43.9%)	33 (31.1%)	NS
HbA1c, %	5.8 ± 0.5	8.0 ± 1.8	<0.0001
HbA1c, mmol/mol	40 ± 3	64 ± 14
Fasting plasma glucose, mg/dL	136 ± 19	180 ± 58	<0.0001
Fasting plasma glucose, mmol/L	7.6 ± 1.1	10.0 ± 3.2
Two-hour plasma glucose, mg/dL	195 ± 64	315 ± 90	<0.0001
Two-hour plasma glucose, mmol/L	10.8 ± 3.6	17.5 ± 5.0
Racial/ethnic group			NS
Mexican Americans	26 (18.7%)	26 (24.5%)
Other Hispanics	15 (10.8%)	9 (8.5%)
Non-Hispanic Whites	79 (56.8%)	48 (45.3%)
Non-Hispanic Blacks	18 (13.0%)	19 (17.9%)
Others	1 (0.7%)	4 (3.8%)

Mean ± standard deviation or with percent; NS, not significant.