Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration

Table 5

Comparison of clinical characteristics of subjects with 2-hour plasma glucose ≥200 mg/dL (≥11.1 mmol/L) stratified by HbA1c < or ≥ 6.5% (48 mmol/mol).

	⁢Diabetes by 2-hour plasma glucose
	HbA1c < 6.5%; (<48 mmol/mol)	HbA1c ≥ 6.5%; (≥48 mmol/mol)
	282	110
Age, year	64 ± 15	60 ± 15	0.01
Gender, female	150 (53.2%)	42 (38.2%)	0.008
Body mass index, kg/m^2	29.7 ± 6.1	33.0 ± 6.6	<0.0001
Systolic blood pressure, mmHg	132 ± 20	132 ± 20	NS
Diastolic blood pressure, mmHg	68 ± 13	70 ± 14	NS
Current smoking, yes	51 (18.1%)	32 (29.1%)	0.02
Alcohol consumption, yes	192 (68.1%)	74 (67.3%)	NS
Family history of diabetes, yes	110 (39.0%)	52 (47.3%)	NS
HbA1c, %	5.7 ± 0.4	7.9 ± 1.8	<0.0001
HbA1c, mmol/mol	39 ± 5	63 ± 18
Fasting plasma glucose, mg/dL	83 ± 20	176 ± 60	<0.0001
Fasting plasma glucose, mmol/L	6.5 ± 1.1	9.8 ± 3.3
Two-hour plasma glucose, mg/dL	232 ± 31	318 ± 82	<0.0001
Two-hour plasma glucose, mmol/L	12.9 ± 1.8	17.7 ± 4.6
Racial/ethnic group			0.004
Mexican Americans	95 (19.5%)	26 (23.6%)
Other Hispanics	26 (9.2%)	9 (8.2%)
Non-Hispanic Whites	172 (61.0%)	50 (45.5%)
Non-Hispanic Blacks	21 (7.5%)	22 (20.0%)
Others	8 (2.8%)	3 (2.7%)

Mean ± standard deviation or n with percent; NS, not significant.