Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways

Figure 7

The schematic diagram summarizes possible mechanisms by which CoQ10 reduces hyperglycemia-induced endothelial progenitor cell damage. In high glucose condition, CoQ10 improved EPCs migration and apoptosis by ROS and caspase 3 downregulation and mitochondrial membrane potential () and Bcl-2 upregulation through HO-1 pathway.