Table 1: Differentially expressed genes from insulin signaling pathway of Id2−/− mice. Genes with significant differences () are shown in bold. Peak phase value (determined by Lomb-Scargle phase values within CIRCA) in circadian time (CT) is provided where gene was identified as a clock control gene. Rhythmic genes identified from CIRCA database of Mouse 1.OST Brown Adipose (Affymetrix).

Insulin signaling arraySymbolRefseqAllMaleFemaleClock control gene-peak phase
Fold change valueFold change valueFold change value

Gene name
AE binding protein 1Aebp1NM_0096361.90.091.60.03
Complement factor D (adipsin)CfdNM_0134592.40.013.60.03
Fructose bisphosphatase 1Fbp1NM_0193951.30.221.60.05
Glucose-6-phosphatase, catalyticG6pcNM_0080611.50.281.50.331.60.02
Growth factor receptor bound protein 10Grb10NM_0103451.50.08
Insulin receptor substrate 1Irs1NM_0105701.40.011.30.071.40.05
Protein tyrosine phosphatase, receptor type, FPtprfNM_0112131.70.052.60.05
Scr homology 2 domain containing transforming protein C1Shc1NM_0113681.250.01

Glucose-6-phosphatase, catalytic, 2G6pc2NM_021331−3.20.08
Insulin-like growth factor 2Igf2NM_010514−1.20.21−1.40.04
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homologKrasNM_021284−1.10.09−1.250.03
Protein kinase C, iotaPrkciNM_008857−1.20.02−1.30.02CT0
ThyroglobulinTgNM_009375−1.80.29−3.50.02