Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas

<div>Prevascularized bioartificial pancreases express insulin degrading enzyme. SPECs, fibroblasts (NHDFs), and endothelial cells (HAMECs) were homogenized in sample loading buffer, resolved by SDS-PAGE, and immunoblotted for insulin degrading enzyme (IDE) and <i>α</i>-tubulin. Robust expression of insulin degrading enzyme was observed both in the cultured cells and in the assembled construct.</div>

Journal of Diabetes Research

fig5

Figure 5

Figure 5: Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas 

Figure 5 | Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascularized Bioartificial Pancreas 