|
| Infections |
| Respiratory | Respiratory symptoms (cough or tachypnea) plus a chest X-ray with changes suggestive of viral or bacterial respiratory infection. |
| Urinary | Urine sample with ≥10 leukocytes/µL [30], temperature > 38.0°C, and not being able to orally tolerate fluids/food. |
| Gastrointestinal | Diarrhea < 7 days, vomiting, and dehydration. |
| Subcutaneous tissue (SCT) | Cellulitis or necrotizing fasciitis in any part of the body except feet. |
| Diabetic foot | Ulceration, infection, and/or gangrene of foot associated with diabetic neuropathy and different grades of peripheral artery disease [21]. |
|
| Metabolic disorders |
| Hypoglycemia | Glucose ≤70 mg/dL (3.9 mmol/L) [21]. |
| Diabetic ketoacidosis | Glucose >250 mg/dL, pH <7.3, and bicarbonate <18 mEq/d [21]. |
| Hyperosmolar state | Glucose >600 mg/dL, pH arterial: >7.30, bicarbonate: >18 mEq/L, anion GAP: variable, mental status: drowsy/coma, few kenotic bodies in the urine and blood, and plasmatic osmolality > 320 mOsm/kg [21]. |
|
| Vascular |
| Stroke | Fast development of clinic signs of changes in the cerebral function or global, with symptoms that persist within 24 hours or more, with no other evidence of vascular origin [21]. |
|
| Renal |
| Acute renal failure | Sudden increase (within 48 hours) of creatinine (Cr)
≥0.3 mg/dL (26.4 micromol/L) of basal or a percentage of increment of Cr of ≥50%; or oliguria of <0.5 mL/kg/hour by more than six hours [31]. |
| Chronic renal failure | Presence of renal damage (urinary albumin excretion ≥30 mg/day) or decrease of the renal function (GFR <60 mL/min/1.73 m2) by three or more months, independent of the cause [32] documented as past medical history plus acute renal failure at the moment of admission (exacerbation). |
|
