Research Article

Inhospital Mortality in Patients with Type 2 Diabetes Mellitus: A Prospective Cohort Study in Lima, Peru

Table 4

Cumulative effect of comorbidities and its association with death: crude and adjusted models using Cox regression.

AliveDeadCrude modelAdjusted modelImputed model
()()HR (95% CI)HR (95% CI)HR (95% CI)

Number of morbidities
 One331 (94.8%)18 (5.2%)1 (Reference)1 (Reference)1 (Reference)
 Two105 (87.5%)15 (12.5%)2.76 (1.36–5.60)7.75 (1.62–37.01)2.39 (1.07–5.32)
 Three or more18 (69.2%)8 (30.8%)7.19 (3.07–16.82)21.12 (4.43–100.86)9.70 (3.56–26.40)

The number of morbidities was calculated by adding proposed causes of hospitalization.
The model was adjusted for gender, age, place of origin, education level, time of disease, hospital admission, treatment, and glycemic control.
The imputed model was adjusted for the same variables listed above; missing values of glycemic control and time of disease were imputed.