Clinical Study

Topical Administration of Pirfenidone Increases Healing of Chronic Diabetic Foot Ulcers: A Randomized Crossover Study

Table 3

Complete healing in the treatment groups.

ā€ƒAll ulcers
(%)
Pirfenidone
(%)
Conventional
(%)

Ulcer healing < 8 weeks
(35 ulcers at the beginning)
13 (37.1)11 (52.4)2 (14.3)0.025

Ulcer healing 8ā€“16 weeks
(22 ulcers at the beginning)
4 (17.4)4 (30.8)00.081