Clinical Study
Topical Administration of Pirfenidone Increases Healing of Chronic Diabetic Foot Ulcers: A Randomized Crossover Study
| | Group 1 | Group 2 | | Weeks 0 to 7 | Weeks 8 to 16 | Weeks 0 to 7 | Weeks 8 to 16 | | Pirfenidone | Conventional treatment | Conventional treatment | Pirfenidone |
| Osteomyelitis | 4 (eliminated) | 0 | 6 (eliminated) | 0 | Hypergranulation | 0 | 0 | 0 | 1 | Thyroid carcinoma | 0 | 0 | 1 (eliminated) | 0 |
| Total AE | 4 | 0 | 7 | 1 |
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