Oxygenation of the Intraportally Transplanted Pancreatic Islet

Figure 7

Islet size distribution stratified by ranges of islet diameter (a). Mean (± standard error, SE) number fractions are actual data from our institution (University of Minnesota) from 23 human islet preparations (high-purity, cultured fractions) prior to clinical transplantation. Mean (± SE) volume fractions are estimated from number fraction data by calculating the mean islet volumes under the assumption that the islets are spherical with a representative radius for that size range. Approximately 20% of the total number of islets were >200 μm in diameter, but these islets account for ~72% of the total transplanted volume of islets (b).